ACCADEMIA NAZIONALE DEI LINCEI

CENTRO LINCEO INTERDISCIPLINARE «BENIAMINO SEGRE»

Convegno internazionale sul tema

BIOINFORMATICS AND COMPUTATIONAL BIOLOGY

1 - 3 OTTOBRE 2004

ROMA

PALAZZINA DELL'AUDITORIO - VIA DELLA LUNGARA, 230

Scientific Committee:

Tom BLUNDELL (University of Cambridge, UK), Peer BORK (European Molecular Biology Laboratory, Heidelberg), Maurizio BRUNORI (Università di Roma “La Sapienza”), Frank GANNON (European Molecular Biology Organization, Heidelberg), Cecilia SACCONE (Università di Bari), Janet THORNTON (European Bioinformatics Institute, Cambridge, UK), Anna TRAMONTANO (Università di Roma “La Sapienza”)

Con il contributo di:

European Molecular Biology Organization

Centro Linceo Interdisciplinare

* * *

Per informazioni:

Anna Tramontano, Dipartimento di Scienze Biochimiche

Tel. 0649910556, Fax 0649910717,

e-mail: anna.tramontano@uniroma1.it

Segreteria:

Anna Anastasi, Centro Linceo Interdisciplinare

Tel. 066833131, Fax 066893616,

e-mail: anastasi@lincei.it

PROGRAMMA

Venerdì 1° ottobre

17.00 Registrazione

18.30 Welcome addresses

Frank GANNON (Heidelberg): EMBO activities

Presiede: Maurizio BRUNORI

19.00 Barry HONIG (New York): Combining bioinformatics and biophysics to understand biological structure and function

Sabato 2 ottobre

COMPUTATIONAL GENOMICS AND MOLECULAR BIOLOGY

Presiede: Sören BRUNAK

9.00 Sören BRUNAK (Copenhagen): Introduction

9.15 Cecilia SACCONE (Bari): Comparative Genomics: tools and theories

9.45 Antoine DANCHIN (Parigi): Living Turing machines

10.15 Giorgio BERNARDI (Napoli): The neo-selectionist theory of Molecular Evolution: a brief report

10.45 Cyrus CHOTHIA (Cambridge, UK): The formation of pathways

11.15 Intervallo

COMPUTATIONAL STRUCTURAL BIOLOGY

Presiede: Anna TRAMONTANO

11.45 Anna TRAMONTANO (Roma): Introduction

12.00 John MOULT (Rockville): SNPs, Protein Structure and Disease

12.30 Janet THORNTON (Cambridge, UK): Towards under-standing enzyme catalysis and evolution through protein structures

13.00 Michael LEVITT (Stanford): Protein Structural Com-parison and Classification

15.00 Frank GANNON (Heidelberg): EMBO matters

COMPUTATIONAL CELL BIOLOGY

Presiede: Alfonso VALENCIA

15.30 Alfonso VALENCIA (Madrid): Introduction

15.45 Dennis BRAY (Cambridge, UK): Bacterial chemo-taxis: using computer models to unravel mechanism

16.15 Shoshana WODAK (Bruxelles): Transcriptional regu-lation of protein complexes in yeast

16.45 Marie-France CARLIER (Gif-sur-Yvette): A bio-mimetic motility assay provides insight into the mechanism of actin-based motility

17.15 Intervallo

INDUSTRY CORNER

Presiede: Cecilia SACCONE

17.45 Leopoldo FRATI (Milano), Pietro LEO (Bari): IBM activities in the Healthcare and Life Sciences domain and specific capabilities and innovative projects developed in Italy

18.15 Frank GANNON (Heidelberg): EMBO matters

Domenica 3 ottobre

9.00 Frank GANNON (Heidelberg): EMBO matters

COMPUTATIONAL MOLECULAR MEDICINE

Presiede: Janet THORNTON

9.30 Janet THORNTON (Cambridge, UK): Introduction

9.45 Antonino CATTANEO (Roma): Neurodegenerative diseases

10.15 Peer BORK (Heidelberg): Function prediction in 4D

10.45 Luis SERRANO (Heidelberg): Prediction of protein interactions based on homology modelling and energy calculation

11.15 Intervallo

11.45 Janet THORNTON (Cambridge, UK): The Biosapiens Network of Excellence

12.30 Tavola rotonda e discussione

Presiede: Tom BLUNDELL (Cambridge, UK)